Table 1. Statistical significance of time- and dose-dependent effects of metformin and IAA94 on U87 cell survival.

Time	Metformin (mM)					IAA94 (μM)
	1	3	10	30	50	1	10	30	100	300
24h	n.s.	n.s.	n.s.	<0.0001	<0.0001	n.s.	n.s.	n.s.	<0.0001	<0.0001
48h	<0.05	<0.0001	<0.0001	<0.0001	<0.0001	n.s.	n.s.	n.s.	<0.0001	<0.0001
72h	<0.0005	<0.0001	<0.0001	<0.0001	<0.0001	n.s.	n.s.	n.s.	<0.0001	<0.0001

Data are obtained comparing treated cell viability with vehicle-treated control cells, in MTT assay.

One-way ANOVA, followed by Dunnett's post hoc test.

n.s.: not significant.