Abstract
Two sesquiterpene lactones, hymenovin and tenulin, were tested for their effect on growth of two strains of Bacillus thuringiensis. Growth of both strains was 98% inhibited by 0.6 mg of tenulin per ml, but only 15 to 20% was inhibited by the same level of hymenovin. Hymenovin appeared to have a mutagenic effect on B. thuringiensis cultures resulting in production of several variant strains. Some of the variant strains had lost their ability to form spores and crystals. Hymenovin also induced B. thuringiensis to produce significant levels of bacteriophage. All variant strains were as susceptible to phage as the parent strain. Although the bactericidal activity of tenulin was two times as great as of hymenovin, tenulin did not appear to have a mutagenic effect on the bacteria.
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- Ivie G. W., Witzel D. A., Herz W., Kannan R., Norman J. O., Rushing D. D., Johnson J. H., Rowe L. D., Veech J. A. Hymenovin. major toxic constituent of Western bitterweed (Hymenoxys odorata DC.) J Agric Food Chem. 1975 Sep-Oct;23(5):841–845. doi: 10.1021/jf60201a051. [DOI] [PubMed] [Google Scholar]
- Ivie G. W., Witzel D. A., Rushing D. D. Toxicity and milk bittering properties of tenulin, the major sesquiterpene lactone constituent of Helenium amarum (bitter sneezeweed). J Agric Food Chem. 1975 Sep-Oct;23(5):845–849. doi: 10.1021/jf60201a012. [DOI] [PubMed] [Google Scholar]
- Kupchan S. M. Recent advances in the chemistry of tumor inhibitors of plant origin. Trans N Y Acad Sci. 1970 Jan;32(1):85–106. doi: 10.1111/j.2164-0947.1970.tb02046.x. [DOI] [PubMed] [Google Scholar]
- de Barjac H., Sisman J., Cosmao-Dumanoir V. Description de 12 bactériophages isolés à partir de Bacillus thuringiensis. C R Acad Sci Hebd Seances Acad Sci D. 1974 Dec 16;279(25):1939–1942. [PubMed] [Google Scholar]