Abstract
A comparison between direct and standardized disk diffusion tests was made on a total of 300 urine specimens containing ≥105 organisms/ml. Of these, 246 represented pure cultures and 54 represented mixed cultures. The number of major discrepancies per organism tested in pure culture was 18 (7.3%) and in mixed cultures it was 23 (42.6%). The percentage of major discrepancies per total number of antimicrobial drug comparisons made was 1.4%. Although this procedure may be of value in selected cases with pure cultures of organisms present in quantities ≥105/ml, its use on a routine basis is not recommended.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Barry A. L., Joyce L. J., Adams A. P., Benner E. J. Rapid determination of antimicrobial susceptibility for urgent clinical situations. Am J Clin Pathol. 1973 May;59(5):693–699. doi: 10.1093/ajcp/59.5.693. [DOI] [PubMed] [Google Scholar]
- Bauer A. W., Kirby W. M., Sherris J. C., Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966 Apr;45(4):493–496. [PubMed] [Google Scholar]
- Kunin C. M. Urinary tract infections. Flow charts (algorithms) for detection and treatment. JAMA. 1975 Aug 4;233(5):458–462. doi: 10.1001/jama.233.5.458. [DOI] [PubMed] [Google Scholar]
- Perez J. R., Gillenwater J. Y. Clinical evaluation of testing immediate antibiotic disk sensitivities in bacteriuria. J Urol. 1973 Oct;110(4):452–456. doi: 10.1016/s0022-5347(17)60248-9. [DOI] [PubMed] [Google Scholar]
- Thornsberry C., Gavan T. L., Sherris J. C., Balows A., Matsen J. M., Sabath L. D., Schoenknecht F., Thrupp L. D., Washington J. A., 2nd Laboratory evaluation of a rapid, automatic susceptibility testing system: report of a collaborative study. Antimicrob Agents Chemother. 1975 Apr;7(4):466–480. doi: 10.1128/aac.7.4.466. [DOI] [PMC free article] [PubMed] [Google Scholar]