Table 2.
Study and Patient Characteristics.
| Authors | Treatment | Previous Proceduresa (%) | Concomitant Procedures | n | Mean Age (Years) | Mean Defect Size (cm2) | Follow-up (Months) | Lesion |
|---|---|---|---|---|---|---|---|---|
| Minas et al.19 | ACI | 90-100 | Osteotomy (30.3%) | 153 | 38.3 | 4.9 | 64.2 | Early OA |
| Ligament reconstruction (2.6%) | ||||||||
| Patella realignment (28.3%) | ||||||||
| Meniscal allograft (4.6%) | ||||||||
| Filardo et al. (2011)15 | ACI | 78 | Osteotomy (6.8%) | 58 | 34.7 | 2.3 | 74.4 | Degenerative |
| Ligament reconstruction (15.5%) | ||||||||
| Menisectomy (15.5%) | ||||||||
| Meniscal implants (6.9%) | ||||||||
| Filardo et al. (2013)16 | ACI | 83% | Osteotomy (30%) | 44 | 42 | 4.0 | 108 | Early OA |
| Ligament reconstruction (6.8%) | ||||||||
| Patella realignment (4.5%) | ||||||||
| Menisectomy (4.5%) | ||||||||
| Ossendorf et al.20 | ACI | 80-100 | Osteotomy (25.0%) | 40 | 36.0 | 5.0 | 24 | Early OA |
| Ligament reconstruction (25.0%) | ||||||||
| Patella realignment (2.5%) | ||||||||
| Capsular shift (2.5%) | ||||||||
| Rosenberger et al.21 | ACI | 90-100 | Osteotomy (21.4%) | 56 | 48.8 | 11.7 | 50.6 | Degenerative |
| Ligament reconstruction (3.6%) | ||||||||
| Patella realignment (25.0%) | ||||||||
| Meniscal allograft (1.8%) | ||||||||
| Hollander et al.17 | ACI | 62 | N/A | 23 | 35.6 | 5.0 | 14.9 | Early OA |
| Bae et al.12 | MF | N/A | Partial menisectomy (75.0%) | 44 | 57.0 | 3.9 | 27.6 | Early OA |
| Bilateral MF (6.8%) | ||||||||
| Brittberg et al.13 | CF | 100 | N/A | 37 | 39.0 | 5.6 | 48 | Early OA |
| De Windt et al.14 | CF | 46-85 | Osteotomy (18.9%) | 47 | 47.0 | 2.7 | 32 | Early OA |
| Menisectomy (38.3%) |
Note: ACI = autologous chondrocyte implantation; N/A = not applicable; MF = microfracture; CF = carbon fibers.
a
Previous procedures: debridement, chondroplasty, marrow stimulation, ligament reconstruction, and menisectomy.