Table 3.

Logistic Regression Analysis for LDDG in Two Susceptible Genes

A. Logistic Regression Analysis.

	Crude		Adjusted
Group	OR	95% CI	OR	95% CI	P Value
Weight	1.02	1.01-1.04	1.03	1.02-1.05	<0.001***
Gender	0.87	0.59-1.27	2.1	1.14-3.87	0.018*
Collision	1.33	0.93-1.9	0.93	0.61-1.42	0.723
D14	2.05	1.2-3.52	2.17	1.10-4.28	0.026*
TC	1.07	0.73-1.57	1.77	1.07-2.93	0.027*
CC	2.79	1.28-6.06	4.38	1.42-13.54	0.010*
D14:gender			0.89	0.28-2.86	0.842
TC:gender			0.39	0.17-0.92	0.032*
CC:gender			0.4	0.08-2.11	0.281

OR = odds ratio; CI = confidence interval; D14 = allele of ASPN gene; TC = genotype of CILP gene; CC = genotype of CILP gene.

The formulated logistic model is as follows:

LDDG = exp(β₀ + β₁W + β₂G + β₃COL + β₄D14 + β₅TC + β₆CC + β₇D14 × G + β₈TC × G + β₉CC × G),

where W, G, COL, D14, TC, and CC denote weight, gender, collision, ASPN D14 allele, CILP TC genotype, and CILP CC genotype, respectively. β_j (j = 1-9) are parameters to be estimated.

^*P < 0.05. ***P < 0.001.