Table 2.

Pearson's (r) and Spearman's (r_s) correlation coefficients between the kynurenine pathway metabolites and brain volumes within the BD (A), and HC (B) groups.

(A). BD	ICV	Total Hipp	Total Amyg
TRP (rs)	0.27	0.20	0.24
KYN (r)	0.15	0.23	0.34*
KYN/TRP (rs)	0.06	0.04	0.11
KA (rs)	0.10	0.24	0.21
3HK (rs)	−0.03	−0.08	0.002
QA (rs)	−0.01	0.04	0.12
KynA/3HK (r)	0.11	0.35**	0.32*
KynA/QA (rs)	0.03	0.25	0.12
CRP (rs)	0.07	−0.05	0.06
(B). HC	ICV	Total Hipp	Total Amyg
TRP (rs)	0.19	0.20	0.28
KYN (r)	−0.25	0.09	0.05
KYN/TRP (rs)	−0.31*	−0.10	−0.11
KynA (rs)	−0.08	−0.03	0.13
3HK (rs)	−0.24	−0.25	−0.30*
QA (rs)	−0.27	−0.12	−0.05
KynA/3HK (r)	0.10	0.11	0.34*
KynA/QA (rs)	0.28	0.13	0.23
CRP (rs)	−0.50**	−0.11	−0.34*

^*p<0.05

^**p<0.01

Abbreviations as in Table 1