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Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1976 Sep;10(3):498–502. doi: 10.1128/aac.10.3.498

Chemical Nature of Agrocin 84 and Its Effect on a Virulent Strain of Agrobacterium tumefaciens

Barbara A McCardell 1, C F Pootjes 1
PMCID: PMC429778  PMID: 984792

Abstract

Agrocin 84, produced by Agrobacterium radiobacter K84, inhibited ribonucleic acid, deoxyribonucleic acid, and protein synthesis and amino acid transport in a susceptible, virulent strain of A. tumefaciens H-38-9. Cell motility was immediately stopped by action of the agrocin, 50% of the cells were killed within 15 min of contact, and the remainder were inhibited. Agrocin 84 is trypsin and pepsin resistant, but chemical analysis indicated a small peptide with a molecular weight of 2,500 containing six different amino acids, including nine molecules of glutamine or glutamic acid and seven molecules of serine.

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Selected References

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