Skip to main content
. 2014 Dec 9;156(2):576–588. doi: 10.1210/en.2014-1026

Figure 8.

Figure 8.

Hypothalamic expression patterns of Pdyn and Opkr1 in the MBH and POA in male and female rats. Relative expression levels of the mRNAs encoding Dyn (Pdyn) and its canonical receptor, KOR (Opkr1), were assayed in male and female rats at different stages of postnatal maturation: infantile, (pre-)prepubertal, and pubertal ages. To allow regional resolution, hypothalamic fragments were dissected and divided into two fragments, containing the POA or the MBH. Values of the specific targets were measured by quantitative PCR, normalized to the expression levels S11 ribosomal protein mRNA, and expressed as percentage change over the expression values in the MBH in infantile (15 d old) male rats. *, P ≤ .05, **, P ≤ .01 in females vs corresponding levels in males (Student t tests). For age-related changes, #, P ≤ .05, ##, P ≤ .01 vs expression values in corresponding infantile (15 d old) groups (two way ANOVA followed by Tukey post hoc test).