Abstract
The in vitro activity of cefaclor and cephalexin against clinical isolates of four bacterial genera was compared. Both agents had a similar range of activity, but cefaclor was significantly more active by weight than cephalexin for most isolates tested.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bill N. J., Washington J. A., 2nd Comparison of in vitro activity of cephalexin, cephradine, and cefaclor. Antimicrob Agents Chemother. 1977 Mar;11(3):470–474. doi: 10.1128/aac.11.3.470. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Boston J. R., Casparis W. R. Estimating savings from hospital merger. Health Serv Res. 1972 Fall;7(3):231–238. [PMC free article] [PubMed] [Google Scholar]
- Klastersky J., Daneau D., Weerts D. Cephradine. Antibacterial activity and clinical effectiveness. Chemotherapy. 1973;18(3):191–204. doi: 10.1159/000221261. [DOI] [PubMed] [Google Scholar]
- Korzeniowski O. M., Scheld W. M., Sande M. A. Comparative pharmacology of cefaclor and cephalexin. Antimicrob Agents Chemother. 1977 Aug;12(2):157–162. doi: 10.1128/aac.12.2.157. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MacLowry J. D., Jaqua M. J., Selepak S. T. Detailed methodology and implementation of a semiautomated serial dilution microtechnique for antimicrobial susceptibility testing. Appl Microbiol. 1970 Jul;20(1):46–53. doi: 10.1128/am.20.1.46-53.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Moellering R. C., Jr, Swartz M. N. Drug therapy: The newer cephalosporins. N Engl J Med. 1976 Jan 1;294(1):24–28. doi: 10.1056/NEJM197601012940106. [DOI] [PubMed] [Google Scholar]
- Scholand J. F., Hodges G. R., Fass R. J., Saslaw S. Clinical evaluation of cephradine, a new oral cephalosporin. Am J Med Sci. 1974 Feb;267(2):111–116. doi: 10.1097/00000441-197402000-00005. [DOI] [PubMed] [Google Scholar]
- Washington J. A. The in vitro spectrum of the cephalosporins. Mayo Clin Proc. 1976 Apr;51(4):237–250. [PubMed] [Google Scholar]
