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. Author manuscript; available in PMC: 2016 Jan 15.
Published in final edited form as: Methods. 2014 Nov 15;72:16–20. doi: 10.1016/j.ymeth.2014.11.007

Fig. 1.

Fig. 1

Proposed 5mC demethylation pathways in mammals. Pathway 1, cleavage of 5fC and 5caC by TDG followed by BER; Pathway 2, direct decarboxylation of 5caC; Pathway 3, deamination of 5hmC followed by BER.