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. Author manuscript; available in PMC: 2016 Jan 15.
Published in final edited form as: Methods. 2014 Nov 6;72:29–40. doi: 10.1016/j.ymeth.2014.10.032

Figure 7. Genome-wide distribution and comparison of DMRs.

Figure 7

(A) A pie chart of locational analysis of DMRs between H1 ESC and brain. The outer pie represented genome-wide background. The inner pie represented distribution of DMRs. The majority of the DMRs were located in intergenic and intragenic regions. Only a small fraction overlapped with CpG islands, although they were enriched. (B) Distribution of DNA methylation levels of predicted DMRs. DMRs were grouped based on their hyper- or hypo-methylated status predicted by M&M. DNA methylation levels predicted by methylCRF (upper panel) and by WGBS (lower panel) were both plotted.