Skip to main content
NCBI home page
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1976 Apr;73(4):1333–1337. doi: 10.1073/pnas.73.4.1333

Pheasant virus: new class of ribodeoxyvirus.

T Hanafusa, H Hanafusa, C E Metroka, W S Hayward, C W Rettenmier, R C Sawyer, R M Dougherty, H S Distefano
PMCID: PMC430267  PMID: 57621

Abstract

Cocultivation of cells derived from embryos of golden pheasants or Amherst pheasants with chicken embryo cells infected with Bryan strain of Rous sarcoma virus resulted in the detection of viruses which appear to be endogenous in these pheasant cells. The pheasant viruses (PV) were similar to avian leukosis-sarcoma viruses (ALSV) in their gross morphology, in the size of their RNA, in the presence of a virion-associated RNA-dependent DNA polymerase (DNA nucleotidyltransferase; deoxynucleoside triphosphate: DNA deoxynucleotidyltransferase; EC 2.7.7.7), and in their growth characteristics. PV also serves as a helper for the glycoprotein-defective Rous sarcoma virus. However, PV was shown to be different from both ALSV and reticuloendotheliosis virus in the following properties: (i) PV does not have ALSV group specific antigens; (ii) the protein composition of PV is different from those of the other two groups of viruses; (iii) PV fails to complement the defective polymerase of alpha type Rous sarcoma virus; and (iv) PV RNA shows no detectable homology with nucleic acids of the other two groups of viruses. Thus, PV appears to be a new class of RNA viruses which contain RNA-dependent DNA polymerase.

Full text

PDF
1333

Images in this article

1335Image
on p.1335
1336Image
on p.1336

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baluda M. A. Widespread presence, in chickens, of DNA complementary to the RNA genome of avian leukosis viruses. Proc Natl Acad Sci U S A. 1972 Mar;69(3):576–580. doi: 10.1073/pnas.69.3.576. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bishop J. M., Levinson W. E., Quintrell N., Sullivan D., Fanshier L., Jackson J. The low molecular weight RNAs of Rous sarcoma virus. I. The 4 S RNA. Virology. 1970 Sep;42(1):182–195. doi: 10.1016/0042-6822(70)90251-5. [DOI] [PubMed] [Google Scholar]
  3. Boettiger D., Love D. N., Weiss R. A. Virus envelope markers in mammalian tropism of avian RNA tumor viruses. J Virol. 1975 Jan;15(1):108–114. doi: 10.1128/jvi.15.1.108-114.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bolognesi D. P., Ishizaki R., Hüper G., Vanaman T. C., Smith R. E. Immunological properties of avian oncornavirus polypeptides. Virology. 1975 Apr;64(2):349–357. doi: 10.1016/0042-6822(75)90111-7. [DOI] [PubMed] [Google Scholar]
  5. Chen J. H., Hanafusa H. Detection of a protein of avian leukoviruses in uninfected chick cells by radioimmunoassay. J Virol. 1974 Feb;13(2):340–346. doi: 10.1128/jvi.13.2.340-346.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Chen J. H., Hayward W. S., Hanafusa H. Avian tumor virus proteins and RNA in uninfected chicken embryo cells. J Virol. 1974 Dec;14(6):1419–1429. doi: 10.1128/jvi.14.6.1419-1429.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Compans R. W., Klenk H. D., Caliguiri L. A., Choppin P. W. Influenza virus proteins. I. Analysis of polypeptides of the virion and identification of spike glycoproteins. Virology. 1970 Dec;42(4):880–889. doi: 10.1016/0042-6822(70)90337-5. [DOI] [PubMed] [Google Scholar]
  8. Crittenden L. B., Wendel E. J., Motta J. V. Interaction of genes controlling resistance to RSV(RAV-O). Virology. 1973 Apr;52(2):373–384. doi: 10.1016/0042-6822(73)90332-2. [DOI] [PubMed] [Google Scholar]
  9. DISTEFANO H. S., DOUGHERTY R. M. VIRUS PARTICLES IN THE NERVE OF REMAK OF CHICK EMBRYOS. J Natl Cancer Inst. 1964 Dec;33:921–934. [PubMed] [Google Scholar]
  10. Fleissner E. Chromatographic separation and antigenic analysis of proteins of the oncornaviruses. I. Avian leukemia-sarcoma viruses. J Virol. 1971 Nov;8(5):778–785. doi: 10.1128/jvi.8.5.778-785.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Fujita D. J., Chen Y. C., Friis R. R., Vogt P. K. RNA tumor viruses of pheasants: characterization of avian leukosis subgroups F and G. Virology. 1974 Aug;60(2):558–571. doi: 10.1016/0042-6822(74)90350-x. [DOI] [PubMed] [Google Scholar]
  12. Haase A. T., Baringer J. R. The structural polypeptides of RNA slow viruses. Virology. 1974 Jan;57(1):238–250. doi: 10.1016/0042-6822(74)90124-x. [DOI] [PubMed] [Google Scholar]
  13. Halpern M. S., Wade E., Rucker E., Baxter-Gabbard K. L., Levine A. S., Friis R. R. A study of the relationship of reticuloendotheliosis virus to the avian leukosis-sarcoma complex of viruses. Virology. 1973 Jun;53(2):287–299. doi: 10.1016/0042-6822(73)90206-7. [DOI] [PubMed] [Google Scholar]
  14. Hanafusa H., Hanafusa T. Noninfectious RSV deficient in DNA polymerase. Virology. 1971 Jan;43(1):313–316. doi: 10.1016/0042-6822(71)90251-0. [DOI] [PubMed] [Google Scholar]
  15. Hanafusa H., Miyamoto T., Hanafusa T. A cell-associated factor essential for formation of an infectious form of Rous sarcoma virus. Proc Natl Acad Sci U S A. 1970 Jun;66(2):314–321. doi: 10.1073/pnas.66.2.314. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Hanafusa T., Hanafusa H. Isolation of leukosis-type virus from pheasant embryo cells: possible presence of viral genes in cells. Virology. 1973 Jan;51(1):247–251. doi: 10.1016/0042-6822(73)90388-7. [DOI] [PubMed] [Google Scholar]
  17. Hanafusa T., Hanafusa H., Miyamoto T., Fleissner E. Existence and expression of tumor virus genes in chick embryo cells. Virology. 1972 Feb;47(2):475–482. doi: 10.1016/0042-6822(72)90283-8. [DOI] [PubMed] [Google Scholar]
  18. Hanafusa T., Hanafusa H., Miyamoto T. Recovery of a new virus from apparently normal chick cells by infection with avian tumor viruses. Proc Natl Acad Sci U S A. 1970 Dec;67(4):1797–1803. doi: 10.1073/pnas.67.4.1797. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Hayward W. S., Hanafusa H. Detection of avian tumor virus RNA in uninfected chicken embryo cells. J Virol. 1973 Feb;11(2):157–167. doi: 10.1128/jvi.11.2.157-167.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Hayward W. S., Hanafusa H. Recombination between endogenous and exogenous RNA tumor virus genes as analyzed by nucleic acid hybridization. J Virol. 1975 Jun;15(6):1367–1377. doi: 10.1128/jvi.15.6.1367-1377.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Kang C. Y., Temin H. M. Lack of sequence homology among RNAs of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken endogenous RNA-directed DNA polymerase activity. J Virol. 1973 Dec;12(6):1314–1324. doi: 10.1128/jvi.12.6.1314-1324.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Kawai S., Hanafusa H. Isolation of defective mutant of avian sarcoma virus. Proc Natl Acad Sci U S A. 1973 Dec;70(12):3493–3497. doi: 10.1073/pnas.70.12.3493. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Mosser A. G. Polypeptide composition of spleen necrosis virus, a reticuloendotheliosis virus. J Virol. 1975 May;15(5):1088–1095. doi: 10.1128/jvi.15.5.1088-1095.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Mountcastle W. E., Compans R. W., Choppin P. W. Proteins and glycoproteins of paramyxoviruses: a comparison of simian virus 5, Newcastle disease virus, and Sendai virus. J Virol. 1971 Jan;7(1):47–52. doi: 10.1128/jvi.7.1.47-52.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Mountcastle W. E., Harter D. H., Choppin P. W. The proteins of visna virus. Virology. 1972 Feb;47(2):542–545. doi: 10.1016/0042-6822(72)90299-1. [DOI] [PubMed] [Google Scholar]
  26. Obijeski J. F., Marchenko A. T., Bishop D. H., Cann B. W., Murphy F. A. Comparative electrophoretic analysis of the virus proteins of four rhabdoviruses. J Gen Virol. 1974 Jan;22(1):21–33. doi: 10.1099/0022-1317-22-1-21. [DOI] [PubMed] [Google Scholar]
  27. Quintrell N., Varmus H. E., Bishop J. M., Nicholson M. O., McAllister R. M. Homologies among the nucleotide sequences of the genomes of C-type viruses. Virology. 1974 Apr;58(2):568–575. doi: 10.1016/0042-6822(74)90090-7. [DOI] [PubMed] [Google Scholar]
  28. Rosenthal P. N., Robinson H. L., Robinson W. S., Hanafusa T., Hanafusa H. DNA in uninfected and virus-infected cells complementary to avian tumor virus RNA. Proc Natl Acad Sci U S A. 1971 Oct;68(10):2336–2340. doi: 10.1073/pnas.68.10.2336. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Scheele C. M., Hanafusa H. Proteins of helper-dependent RSV. Virology. 1971 Aug;45(2):401–410. doi: 10.1016/0042-6822(71)90341-2. [DOI] [PubMed] [Google Scholar]
  30. Schulze I. T. The structure of influenza virus. I. The polypeptides of the virion. Virology. 1970 Dec;42(4):890–904. doi: 10.1016/0042-6822(70)90338-7. [DOI] [PubMed] [Google Scholar]
  31. TRAGER W. A new virus of ducks interfering with development of malaria parasite (Plasmodium lophurae). Proc Soc Exp Biol Med. 1959 Jul;101(3):578–582. doi: 10.3181/00379727-101-25023. [DOI] [PubMed] [Google Scholar]
  32. Temin H. M. On the origin of RNA tumor viruses. Annu Rev Genet. 1974;8:155–177. doi: 10.1146/annurev.ge.08.120174.001103. [DOI] [PubMed] [Google Scholar]
  33. Varmus H. E., Weiss R. A., Friis R. R., Levinson W., Bishop J. M. Detection of avian tumor virus-specific nucleotide sequences in avian cell DNAs (reassociation kinetics-RNA tumor viruses-gas antigen-Rous sarcoma virus, chick cells). Proc Natl Acad Sci U S A. 1972 Jan;69(1):20–24. doi: 10.1073/pnas.69.1.20. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Weiss R. A., Boettiger D., Love D. N. Phenotypic mixing between vesicular stomatitis virus and avian RNA tumor viruses. Cold Spring Harb Symp Quant Biol. 1975;39(Pt 2):913–918. doi: 10.1101/sqb.1974.039.01.106. [DOI] [PubMed] [Google Scholar]
  35. Závada J. VSV pseudotype particles with the coat of avian myeloblastosis virus. Nat New Biol. 1972 Nov 22;240(99):122–124. doi: 10.1038/newbio240122a0. [DOI] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES