Abstract
The membrane penicillinase (EC 3.5.2.6; penicillin amido-beta-lactamhydrolase) of Bacillus licheniforis 749/C, which appears to be an intermediate in the formation of the exoenzyme, is a phospholipoprotein that carries an NH2-terminal chain of 24 amino acids (only serine, glycine, aspartic acid, asparagine, glutamic acid, and glutamine) and a phosphatidylserine that is not present in the exoenzyme.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Ambler R. P., Meadway R. J. Chemical structure of bacterial penicillinases. Nature. 1969 Apr 5;222(5188):24–26. doi: 10.1038/222024a0. [DOI] [PubMed] [Google Scholar]
- Dancer B. N., Lampen J. O. In vitro synthesis of hydrophobic penicillinase in extracts of Bacillus licheniforms 749/C. Biochem Biophys Res Commun. 1975 Oct 27;66(4):1357–1364. doi: 10.1016/0006-291x(75)90509-4. [DOI] [PubMed] [Google Scholar]
- Jukes T. H. Mutations in proteins and base changes in condons. Biochem Biophys Res Commun. 1975 Sep 2;66(1):1–8. doi: 10.1016/s0006-291x(75)80286-5. [DOI] [PubMed] [Google Scholar]
- Lampen J. O. Cell-bound penicillinase of Bacillus licheniformis; properties and purification. J Gen Microbiol. 1967 Aug;48(2):249–259. doi: 10.1099/00221287-48-2-249. [DOI] [PubMed] [Google Scholar]
- Lampen J. O. Movement of extracellular enzymes across cell membranes. Symp Soc Exp Biol. 1974;(28):351–374. [PubMed] [Google Scholar]
- Lampen J. O. Release of penicillinase by Bacillus licheniformis. J Gen Microbiol. 1967 Aug;48(2):261–268. doi: 10.1099/00221287-48-2-261. [DOI] [PubMed] [Google Scholar]
- Lande M. A., Adesnik M., Sumida M., Tashiro Y., Sabatini D. D. Direct association of messenger RNA with microsomal membranes in human diploid fibroblasts. J Cell Biol. 1975 Jun;65(3):513–528. doi: 10.1083/jcb.65.3.513. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Matsuo H., Fujimoto Y., Tatsuno T. A novel method for the determination of C-terminal amino acid in polypeptides by selective tritium labelling. Biochem Biophys Res Commun. 1966 Jan 4;22(1):69–74. doi: 10.1016/0006-291x(66)90604-8. [DOI] [PubMed] [Google Scholar]
- Milcarek C., Penman S. Membrane-bound polyribosomes in HeLa cells: association of polyadenylic acid with membranes. J Mol Biol. 1974 Oct 25;89(2):327–338. doi: 10.1016/0022-2836(74)90522-1. [DOI] [PubMed] [Google Scholar]
- Peterson J. D., Nehrlich S., Oyer P. E., Steiner D. F. Determination of the amino acid sequence of the monkey, sheep, and dog proinsulin C-peptides by a semi-micro Edman degradation procedure. J Biol Chem. 1972 Aug 10;247(15):4866–4871. [PubMed] [Google Scholar]
- Pisano J. J., Bronzert T. J. Analysis of amino acid phenylthiohydantoins by gas chromatography. J Biol Chem. 1969 Oct 25;244(20):5597–5607. [PubMed] [Google Scholar]
- Roseau G., Pantel P. Révélation colorée des spots de phénylthiohydantoïne d'acides aminés. J Chromatogr. 1969 Oct 28;44(2):392–395. doi: 10.1016/s0021-9673(01)92553-1. [DOI] [PubMed] [Google Scholar]
- Sawai T., Lampen J. O. Purification and characteristics of plasma membrane penicillinase from Bacillus licheniformis 749-C. J Biol Chem. 1974 Oct 10;249(19):6288–6294. [PubMed] [Google Scholar]
- Sherratt D. J., Collins J. F. Analysis by transformation of the penicillinase system in Bacillus licheniformis. J Gen Microbiol. 1973 May;76(1):217–230. doi: 10.1099/00221287-76-1-217. [DOI] [PubMed] [Google Scholar]
- Woods K. R., Wang K. T. Separation of dansyl-amino acids by polyamide layer chromatography. Biochim Biophys Acta. 1967 Feb 21;133(2):369–370. doi: 10.1016/0005-2795(67)90078-5. [DOI] [PubMed] [Google Scholar]
- Yamamoto S., Lampen J. O. Membrane penicillinase of Bacillus licheniformis 749/C, a phospholipoprotein. J Biol Chem. 1975 Apr 25;250(8):3212–3213. [PubMed] [Google Scholar]