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Sunitinib concentrations at the end of the experiment in mice bearing HT-29 parental (HT-29PAR) or HT-29 sunitinib resistant (HT-29SUN) tumors. Sunitinib concentrations intratumoral (A), in skin (B) and in serum (C) were measured with liquid chromatography - tandem mass spectrometry (LC-MS/MS). Results are shown as individual mice (n = 8) with median indicated.
