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. Author manuscript; available in PMC: 2015 Jul 22.
Published in final edited form as: Nature. 2014 Nov 5;517(7535):497–500. doi: 10.1038/nature13896

Extended Data Fig. 7. S6k deletion decreases intestinal regeneration.

Extended Data Fig. 7

Graphical representation of findings, and boxplot showing that murine intestinal regeneration following irradiation is dependent on S6K. Animals were exposed to 14Gy γ-irradiation, and intestinal regeneration was calculated 72hrs after exposure by counting the number of viable crypts and multiplying that by the average size of the regenerating crypts. Relative regeneration was calculated by comparing each group to WT regeneration. Rapamycin treatment arm is reproduced from Fig.4 for visual clarity. Whiskers are max and min, black line is median (n=6 per group, *p-value=0.034, Mann Whitney U test).