Table 3. Predictors for changes in parent reported health-related quality of life from 10 to 18 years of age for EP- and term-born children.
| Response variable | Explanatory variablesa | ||
|---|---|---|---|
| CHQ-PF50 scale changes (score range 0–100) |
Genderb | EP- vs. term-born (n = 57) b (95%CI) |
CBCL total problem score at 10 yearsc b (95% CI) |
| Physical functioning | −2.0 (−6.7, 2.7) | −0.1 (−0.2, 0.1) | |
| Role/social – emotional/behavioral | 0.8 (−9.2, 10.9) | −0.7 (−1.0, −0.3)*** | |
| Role/social – physical | 0.9 (−6.0, 7.8) | −0.1 (−0.3, 0.1) | |
| Bodily paind | 7.1 (−4.1, 18.3) | −0.4 (−0.7, −0.02)* | |
| Behavior | 1.9 (−5.9, 9.6) | −0.2 (−0.5, 0.03) | |
| Mental health | Boys Girls |
8.5e (−1.1, 18.2) −4.8 (−10.8, 1.2) |
−0.3 (−0.5, −0.04)* |
| Self-esteem | Boys Girls |
19.3f (8.9, 29.6) −5.0 (−11.6, 1.5) |
−0.3 (−0.5, −0.1)** |
| General health | −2.7 (−10.0, 4.4) | −0.03(−0.2, 0.2) | |
| Parental impact–emotional | 1.5 (−6.8, 9.8) | −0.3 (−0.6, −0.1)* | |
| Parental impact–time | 0.9 (−2.9, 4.8) | −0.1 (−0.3, 0.01) | |
| Family activity | 1.4 (−6.4, 9.3) | −0.2 (−0.5, 0.1) | |
| Family cohesion | 3.5 (−6.5, 13.5) | −0.4 (−0.6, −0.1)* | |
Notes.
EP = extremely preterm, CHQ = Child Health Questionnaire-Parent Form50.
a
Mixed linear regression model adjusted for CHQ-scores at 10 years, gender, maternal education at 10 years and attention deficit hyperactivity disorder/mild mental retardation (n = 5). Positive b indicates improved outcome.
b
Estimates are given specifically for boys and girls when there was a significant interaction group by gender.
c
Child Behavior Checklist—total problem score: negative association of total problem score indicates that high level of problems at 10 years of age predicts less improvement in CHQ-scores to 18 years.
d
Two missing.
e
Interaction p-value = 0.017.
f
Interaction p-value < 0.001.
*
p ≤ 0.05.
**
p ≤ 0.01.
***
p ≤ 0.001.