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. 1976 Aug;73(8):2757–2761. doi: 10.1073/pnas.73.8.2757

Defective thymine dimer excision by cell-free extracts of xeroderma pigmentosum cells.

K Mortelmans, E C Friedberg, H Slor, G Thomas, J E Cleaver
PMCID: PMC430730  PMID: 1066689

Abstract

Crude extracts of normal human diploid fibroblasts and of human peripheral blood lymphocytes excise thymine dimers from purified ultraviolet-irradiated DNA, or from the DNA presumably present as chromatin in unfractionated cell-free preparations of cells that had been labeled with [3H]thymidine. Extracts of xeroderma pigmentosum cells from complementation groups A, C, and D also excise thymine dimers from purified DNA, but extracts of group A cells do not excise dimers from the DNA of radioactively labeled unfractionated cell-free preparations.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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