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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1976 Aug;73(8):2767–2769. doi: 10.1073/pnas.73.8.2767

Inhibition of erythrocyte phosphate transport by high pressures.

R B Murphy, W F Libby
PMCID: PMC430734  PMID: 1066690

Abstract

Pressures of 200-1000 atmospheres (20-100 MPa) are found to decrease significantly the amount of phosphate (H32PO4-2)transported into the rabbit erythrocyte under otherwise physiological conditions. Such compression does not cause irreversible morphological changes or result in membrane disruption. The findings are interpreted in terms of a lipid phase transition induced by the high pressure, which is propagated to the associated phosphate transport system by a physical mechanism.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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