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. 1977 Apr;74(4):1492–1496. doi: 10.1073/pnas.74.4.1492

Molecular properties of the nerve growth factor secreted by L cells.

N J Pantazis, M H Blanchard, B G Arnason, M Young
PMCID: PMC430813  PMID: 266190

Abstract

The molecular size and stability of the nerve growth factor (NGF) secreted in culture by L cells have been studied by sedimentation and gel filtration chromatography. Results indicate that L cell NGF has a molecular weight of 160,000. It contains as part of its structure a protein component that is biologically, immunologically, and electrophoretically indistinguishable from the biologically active factor purified from mouse submandibular glands. However, unlike pure gland NGF, L cell NGF is highly stable in solution, and this finding indicates that L cell NGF is a form of the factor different from that previously described.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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