Table 3.
Haemodynamic and pacing parameters measured with each pacing mode
| Baseline (intrinsic) | AAI | DDD RVA −20 ms | DDD RVA −40 ms | DDD RValt −20 ms | DDD RValt −40 ms | DDD BiRV −20 ms | DDD BiRV −40 ms | P value (ANOVA) | |
|---|---|---|---|---|---|---|---|---|---|
| CO (L/min) | 4.7 ± 1.2† | 5.5 ± 0.9 | 5.8 ± 1.3* | 5.9 ± 1.3 | 6.4 ± 1.7* | 6.1 ± 1.4 | 5.9 ± 1.5 | 5.9 ± 1.3 | 0.003 |
| CI (L/min/m2) | 2.7 ± 0.7† | 3.2 ± 0.5 | 3.4 ± 0.8 | 3.5 ± 0.9 | 3.7 ± 1 | 3.6 ± 0.9 | 3.5 ± 0.9 | 3.5 ± 0.8 | 0.004 |
| SV (mL) | 58 ± 16† | 61 ± 10 | 63 ± 13 | 64 ± 13 | 68 ± 17 | 66 ± 14 | 65 ± 15 | 65 ± 13 | 0.01 |
| MAP (mmHg) | 70 ± 11† | 74 ± 10 | 72 ± 10 | 73 ± 9 | 72 ± 10 | 73 ± 10 | 74 ± 9 | 74 ± 10 | 0.49 |
| QRS (ms) | 136 ± 26 | 116 ± 18 | 138 ± 20 | 143 ± 22 | 127 ± 20 | 132 ± 25 | 132 ± 25 | 129 ± 29 | 0.16 |
All forms of pacing, including AAI pacing, generated increases of CO significantly above baseline; however, DDD RV alternate site pacing was found to generate the greatest increase in all measured parameters. There was no significant difference in MAP or QRS duration in the cohort with pacing.
†Not included in repeated-measures ANOVA.
*P = 0.018 when comparing CO DDD RValt with AAI pacing.