Table 1.
Estimating risk under interventions using the g-formula with the hypothetical example given in methods section of the main text.
G-formula component | Value |
---|---|
Conditional probabilities | |
| |
First 5 years | PR(exposed): 0.5 |
Risk among exposed: 0.025 | |
Risk among unexposed: 0.025 | |
Last 5 years | Pr(exposed): 0.5 |
Risk among exposed: 0.060 | |
Risk among unexposed: 0.051 | |
Risk under interventions | |
Observed/Natural course | 0.051*(1/2)*(1-0.025*(1/2)) + 0.025*(1/2) + |
0.060*(1/2)*(1-0.025*(1/2)) + 0.025*(1/2) = 0.080 | |
Always exposed | 0.051*(0)*(1-0.025*(0)) + 0.025*(0) + |
0.060*(1)*(1-0.025*(1)) + 0.025*(1) = 0.084 | |
Never exposed | 0.051*(1)*(1-0.025*(1)) + 0.025*(1) + |
0.060*(0)*(1-0.025*(0)) + 0.025*(0) = 0.075 | |
Expose if survive to year 5 | 0.051*(0)*(1-0.025*(0)) + 0.025*(1/2) + |
0.060*(1)*(1-0.025*(1)) + 0.025*(1/2) = 0.084 |