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. 1976 Nov;73(11):3937–3941. doi: 10.1073/pnas.73.11.3937

Activation of chromatin by acetylation of histone side chains.

K Marushige
PMCID: PMC431273  PMID: 1069278

Abstract

The ability of calf thymus chromatin to support DNA-dependent RNA synthesis is markedly increased by modification of the histones with acetic anhydride. The extent of chemical acetylation of histones H2a, H2b, H3, and H4 required for the increase of template activity of the chromatin is within that which can be achieved enzymatically in the cell. The evidence suggests that the acetylation of histone side chains stimulates the rate of chain elongation during transcription of chromatin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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