Fig. 1.
WNV infection in THP-1 cells and THP-1 macrophages. THP-1 cells (A) and THP-1 macrophages (B) were infected with WNV NY99 and WNV NS4B-P38G mutant at a MOI of 5. A- B. The viral titers at indicated time points post-infection were measured by using a plaque assay. C. Viral titer at 24h post-infection was measured by a Q-PCR assay. Data are presented as means ± SEM, n = 4 -6. *P < 0.05 or **P < 0.01 for NY99 vs. NS4B-P38G. §§ P < 0.01 for THP-1 vs. THP-1 macrophages. Results presented are one representative of two similar experiments.