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. 1977 Jul;74(7):2848–2849. doi: 10.1073/pnas.74.7.2848

Thermosensitive step associated with transfer of the Ti plasmid during conjugation: Possible relation to transformation in crown gall

Jacques Tempé *, Annik Petit *, Marcelle Holsters †, Marc van Montagu †, Jeff Schell †
PMCID: PMC431316  PMID: 16592419

Abstract

It is reported here that transfer by means of a conjugative process of an oncogenic plasmid from a virulent strain of Agrobacterium tumefaciens to a strain of that organism that had been cured of the plasmid is thermosensitive. Since the thermosensitive step found in the conjugative process appears similar in every respect to a thermosensitive step that is involved in the transformation of a normal cell to a tumor cell in the crown gall disease of plants, it is suggested that the observed results may reflect the existence of a thermosensitive step that is common to these two processes.

Keywords: plant tumors, octopine

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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