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. 1976 Nov;73(11):4159–4163. doi: 10.1073/pnas.73.11.4159

Heat mutagenesis in bacteriophage T4: the transversion pathway.

P M Bingham, R H Baltz, L S Ripley, J W Drake
PMCID: PMC431367  PMID: 1069305

Abstract

Heat induces transversions (as well as transitions) at G-C base pairs in bacteriophage T4. The target base for transversions is guanine,which is converted to a product which is sometimes replicated and transcribed as a pyrimidine.A model for this process is proposed in which the deoxyguanosine glycosidic bond migrates from N9 to N2: the resulting deoxyneoguanosine may pair with normal guanine to produce G-C leads to C-G transversions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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