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. 1976 Dec;73(12):4613–4617. doi: 10.1073/pnas.73.12.4613

Single burst study of rec- and red-mediated recombination in bacteriophage lambda.

P V Sarthy, M Meselson
PMCID: PMC431566  PMID: 1070013

Abstract

Single bursts from three-point crosses of bacteriophage lambda were analyzed for recombination of markers several thousand nucleotide pairs apart. Single recombination, mediated by the rec system of Escherichia coli, is usually reciprocal. Double recombinants are also significantly correlated in single bursts, although the correlation is weaker than for reciprocal singles. Reciprocity is not found in crosses mediated by the lambda red system. With respect to certain other paraments of recombination, the two systems appear to be alike. Double recombinants usually result from one event, not from two independent single recombinations, and their average clone size is about half that of single recombinants. The results are discussed in terms of current molecular models of recombination.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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