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. 1977 Dec;74(12):5314–5317. doi: 10.1073/pnas.74.12.5314

Experimental evidence for a kinetic and electrochemical memory in enzyme membranes.

D Thomas, J N Barbotin, A David, J F Hervagault, J L Romette
PMCID: PMC431699  PMID: 23533

Abstract

The existence of hysteresis phenomena in artificial enzyme membranes due to the coupling of simple kinetic enzyme properties with diffusion transport processes is reported. The intramembrane pH of a urease coating on the surface of a glass pH electrode exhibits a hysteresis loop when the pH of the bulk solution varies cyclically. The steady-state potential of a urease membrane, as a function of the substrate concentration in the bulk solution, also exhibits a memory effect. The influence of the membrane's history on its overall behavior is visualized by electron microscopy. We interpret the results in terms of a coupling between the enzyme reactions and diffusion processes, without taking into account molecular effects.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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