Table 2. Circulating humoral factors at baseline.
| Variable | Premenopausal (n = 24) | Early perimenopausal (n = 21) | Late perimenopausal (n = 21) | Postmenopausal (n = 31) | P |
|---|---|---|---|---|---|
| Oxidized LDL, U/L | 43.7 (17.9) | 44.0 (12.0) | 46.2 (17.3) | 52.7 (18.4) | 0.27 |
| TAS (saline), mmol/L | 1.43 (0.22) | 1.35 (0.14) | 1.30 (0.13) | 1.31 (0.14) | 0.09 |
| TAS (ascorbic acid), mmol/L | 2.82 (0.50) | 2.59 (0.51) | 2.56 (0.37) | 2.57 (1.18) | 0.74 |
| Glutathione peroxidase, U/L | 6,218 (1,845) | 7,259 (1,532) | 6,587 (1,376) | 7,250 (1,736) | 0.16 |
| Norepinephrine, pmol/L | 1,047 (394) | 1,394 (477) | 1,479 (672) | 1,567 (736) | 0.006 |
| Endothelin-1, pg/mLa | 5.4 (4.4-6.0) | 5.6 (5.1-6.7) | 5.7 (5.3-6.6) | 6.2 (5.3-7.0) | 0.06 |
| IL-6, pg/mLa | 0.67 (0.54-1.32) | 0.76 (0.62-1.29) | 0.90 (0.49-1.32) | 0.83 (0.66-1.22) | 0.92 |
| C-reactive protein (saline), mg/dLa | 0.68 (0.32-2.38) | 1.03 (0.70-2.21) | 0.89 (0.47-1.61) | 1.24 (0.67-2.36) | 0.17 |
| C-reactive protein (ascorbic acid), mg/dLa | 0.45 (0.24-0.67) | 0.93 (0.63-2.04) | 0.86 (0.45-1.46) | 1.09 (0.47-1.59) | 0.14 |
Data are presented as mean (SD), unless otherwise stated.
LDL, low-density lipoprotein; TAS, total antioxidant status; IL, interleukin.
a
Data are presented as median (interquartile range).