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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1977 Oct;74(10):4552–4556. doi: 10.1073/pnas.74.10.4552

Perturbation of chloroplast DNA amounts and chloroplast gene transmission in Chlamydomonas reinhardtii by 5-fluorodeoxyuridine

Edwin A Wurtz *,, John E Boynton *,, Nicholas W Gillham
PMCID: PMC431984  PMID: 16592455

Abstract

5-Fluorodeoxyuridine selectively decreases the rate of chloroplast DNA replication in Chlamydomonas resulting after several generations of growth in equilibrium levels as low as one-seventh of normal. When the maternal parent is treated prior to mating, the decrease of chloroplast DNA appears to perturb the normal maternal transmission of chloroplast genes, dramatically increasing the proportion of exceptional zygotes transmitting chloroplast genes from the paternal parent.

Keywords: organelle genetics, DNA replication inhibition

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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