There are errors in Table 3. Please view the corrected Table 3 here.
Table 3. Normative age-related total testosterone reference values in nmol/L.
Ages are in years; column headings are percentiles.
| Age | 1 | 2.5 | 10 | 20 | 30 | 40 | 50 | 60 | 70 | 80 | 90 | 97.5 | 99 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3 | 0.0 | 0.0 | 0.0 | 0.1 | 0.2 | 0.2 | 0.4 | 0.6 | 0.6 | 0.7 | 0.8 | 0.9 | 1.0 |
| 4 | 0.0 | 0.0 | 0.1 | 0.1 | 0.2 | 0.2 | 0.4 | 0.6 | 0.6 | 0.7 | 0.8 | 0.9 | 1.0 |
| 5 | 0.0 | 0.0 | 0.1 | 0.1 | 0.2 | 0.2 | 0.4 | 0.6 | 0.6 | 0.7 | 0.8 | 0.8 | 1.0 |
| 6 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 0.2 | 0.3 | 0.5 | 0.6 | 0.6 | 0.7 | 0.8 | 0.9 |
| 7 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 0.3 | 0.5 | 0.5 | 0.6 | 0.7 | 0.7 | 0.9 |
| 8 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.2 | 0.4 | 0.5 | 0.5 | 0.6 | 0.7 | 0.9 |
| 9 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.5 | 0.5 | 0.6 | 0.7 | 0.8 | 1.0 |
| 10 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.3 | 0.7 | 0.8 | 0.9 | 1.0 | 1.2 | 1.4 |
| 11 | 0.0 | 0.0 | 0.0 | 0.2 | 0.3 | 0.3 | 0.7 | 1.3 | 1.4 | 1.6 | 1.9 | 2.1 | 2.6 |
| 12 | 0.0 | 0.3 | 0.5 | 0.8 | 1.0 | 1.1 | 1.7 | 2.8 | 3.1 | 3.4 | 3.9 | 4.3 | 5.2 |
| 13 | 0.6 | 1.4 | 1.7 | 2.2 | 2.5 | 2.7 | 3.8 | 5.9 | 6.4 | 7.0 | 8.0 | 8.8 | 10.3 |
| 14 | 1.8 | 3.0 | 3.6 | 4.4 | 4.8 | 5.2 | 6.9 | 10.5 | 11.4 | 12.4 | 14.0 | 15.3 | 18.0 |
| 15 | 2.9 | 4.6 | 5.6 | 6.6 | 7.3 | 7.9 | 10.3 | 15.4 | 16.5 | 18.0 | 20.2 | 22.1 | 25.9 |
| 16 | 3.7 | 5.9 | 7.0 | 8.3 | 9.2 | 9.8 | 12.9 | 19.0 | 20.4 | 22.2 | 24.9 | 27.2 | 31.7 |
| 17 | 4.1 | 6.6 | 7.8 | 9.3 | 10.3 | 11.1 | 14.4 | 21.1 | 22.6 | 24.6 | 27.5 | 30.0 | 34.9 |
| 18 | 4.4 | 7.0 | 8.3 | 9.8 | 10.8 | 11.7 | 15.2 | 22.0 | 23.6 | 25.6 | 28.5 | 31.1 | 36.1 |
| 19 | 4.6 | 7.2 | 8.5 | 10.0 | 11.1 | 11.9 | 15.4 | 22.2 | 23.7 | 25.7 | 28.6 | 31.1 | 36.1 |
| 20 | 4.7 | 7.3 | 8.6 | 10.1 | 11.1 | 11.9 | 15.4 | 21.9 | 23.5 | 25.4 | 28.2 | 30.7 | 35.5 |
| 21 | 4.8 | 7.3 | 8.6 | 10.0 | 11.0 | 11.8 | 15.2 | 21.6 | 23.0 | 24.9 | 27.6 | 30.0 | 34.7 |
| 22 | 4.9 | 7.3 | 8.5 | 10.0 | 10.9 | 11.7 | 15.0 | 21.2 | 22.6 | 24.4 | 27.0 | 29.3 | 33.8 |
| 23 | 4.9 | 7.3 | 8.5 | 9.9 | 10.8 | 11.5 | 14.8 | 20.7 | 22.1 | 23.9 | 26.4 | 28.7 | 33.1 |
| 24 | 4.9 | 7.2 | 8.4 | 9.8 | 10.7 | 11.4 | 14.5 | 20.4 | 21.7 | 23.4 | 25.9 | 28.1 | 32.3 |
| 25 | 4.9 | 7.2 | 8.3 | 9.7 | 10.6 | 11.3 | 14.3 | 20.0 | 21.3 | 23.0 | 25.4 | 27.6 | 31.7 |
| 26 | 5.0 | 7.2 | 8.3 | 9.6 | 10.4 | 11.1 | 14.1 | 19.7 | 21.0 | 22.6 | 25.0 | 27.1 | 31.2 |
| 27 | 4.9 | 7.1 | 8.2 | 9.5 | 10.3 | 11.0 | 14.0 | 19.5 | 20.7 | 22.3 | 24.7 | 26.7 | 30.7 |
| 28 | 4.9 | 7.1 | 8.2 | 9.4 | 10.3 | 10.9 | 13.8 | 19.2 | 20.5 | 22.1 | 24.4 | 26.4 | 30.4 |
| 29 | 4.9 | 7.0 | 8.1 | 9.3 | 10.2 | 10.8 | 13.7 | 19.1 | 20.3 | 21.8 | 24.2 | 26.2 | 30.1 |
| 30 | 4.9 | 7.0 | 8.0 | 9.3 | 10.1 | 10.8 | 13.6 | 18.9 | 20.1 | 21.7 | 24.0 | 25.9 | 29.8 |
| 31 | 4.9 | 6.9 | 8.0 | 9.2 | 10.0 | 10.7 | 13.5 | 18.8 | 20.0 | 21.5 | 23.8 | 25.8 | 29.6 |
| 32 | 4.8 | 6.9 | 7.9 | 9.1 | 10.0 | 10.6 | 13.4 | 18.7 | 19.9 | 21.4 | 23.7 | 25.6 | 29.4 |
| 33 | 4.8 | 6.8 | 7.9 | 9.1 | 9.9 | 10.6 | 13.3 | 18.6 | 19.8 | 21.3 | 23.6 | 25.5 | 29.3 |
| 34 | 4.8 | 6.8 | 7.8 | 9.0 | 9.9 | 10.5 | 13.3 | 18.5 | 19.7 | 21.2 | 23.5 | 25.4 | 29.2 |
| 35 | 4.7 | 6.8 | 7.8 | 9.0 | 9.8 | 10.5 | 13.2 | 18.4 | 19.6 | 21.2 | 23.4 | 25.4 | 29.2 |
| 36 | 4.7 | 6.7 | 7.8 | 9.0 | 9.8 | 10.4 | 13.2 | 18.4 | 19.6 | 21.1 | 23.4 | 25.3 | 29.1 |
| 37 | 4.7 | 6.7 | 7.7 | 8.9 | 9.7 | 10.4 | 13.1 | 18.4 | 19.6 | 21.1 | 23.3 | 25.3 | 29.1 |
| 38 | 4.6 | 6.7 | 7.7 | 8.9 | 9.7 | 10.3 | 13.1 | 18.3 | 19.5 | 21.1 | 23.3 | 25.3 | 29.1 |
| 39 | 4.6 | 6.6 | 7.7 | 8.9 | 9.7 | 10.3 | 13.1 | 18.3 | 19.5 | 21.1 | 23.3 | 25.3 | 29.1 |
| 40 | 4.5 | 6.6 | 7.6 | 8.8 | 9.6 | 10.3 | 13.0 | 18.3 | 19.5 | 21.1 | 23.3 | 25.3 | 29.2 |
| 41 | 4.5 | 6.5 | 7.6 | 8.8 | 9.6 | 10.2 | 13.0 | 18.3 | 19.5 | 21.1 | 23.4 | 25.3 | 29.2 |
| 42 | 4.5 | 6.5 | 7.6 | 8.8 | 9.6 | 10.2 | 13.0 | 18.3 | 19.6 | 21.1 | 23.4 | 25.4 | 29.3 |
| 43 | 4.4 | 6.5 | 7.5 | 8.7 | 9.5 | 10.2 | 13.0 | 18.3 | 19.6 | 21.1 | 23.4 | 25.4 | 29.3 |
| 44 | 4.4 | 6.4 | 7.5 | 8.7 | 9.5 | 10.2 | 13.0 | 18.4 | 19.6 | 21.2 | 23.5 | 25.5 | 29.4 |
| 45 | 4.4 | 6.4 | 7.5 | 8.7 | 9.5 | 10.2 | 13.0 | 18.4 | 19.6 | 21.2 | 23.5 | 25.6 | 29.5 |
| 46 | 4.3 | 6.4 | 7.4 | 8.7 | 9.5 | 10.1 | 13.0 | 18.4 | 19.7 | 21.2 | 23.6 | 25.6 | 29.6 |
| 47 | 4.3 | 6.3 | 7.4 | 8.6 | 9.5 | 10.1 | 13.0 | 18.4 | 19.7 | 21.3 | 23.6 | 25.7 | 29.7 |
| 48 | 4.2 | 6.3 | 7.4 | 8.6 | 9.4 | 10.1 | 13.0 | 18.5 | 19.7 | 21.3 | 23.7 | 25.8 | 29.8 |
| 49 | 4.2 | 6.3 | 7.4 | 8.6 | 9.4 | 10.1 | 13.0 | 18.5 | 19.8 | 21.4 | 23.8 | 25.9 | 29.9 |
| 50 | 4.2 | 6.3 | 7.3 | 8.6 | 9.4 | 10.1 | 13.0 | 18.5 | 19.8 | 21.4 | 23.9 | 25.9 | 30.0 |
| 51 | 4.1 | 6.2 | 7.3 | 8.6 | 9.4 | 10.1 | 13.0 | 18.6 | 19.9 | 21.5 | 23.9 | 26.0 | 30.1 |
| 52 | 4.1 | 6.2 | 7.3 | 8.5 | 9.4 | 10.1 | 13.0 | 18.6 | 19.9 | 21.6 | 24.0 | 26.1 | 30.3 |
| 53 | 4.0 | 6.2 | 7.3 | 8.5 | 9.4 | 10.0 | 13.0 | 18.6 | 20.0 | 21.6 | 24.1 | 26.2 | 30.4 |
| 54 | 4.0 | 6.2 | 7.2 | 8.5 | 9.4 | 10.0 | 13.0 | 18.7 | 20.0 | 21.7 | 24.2 | 26.3 | 30.5 |
| 55 | 4.0 | 6.1 | 7.2 | 8.5 | 9.3 | 10.0 | 13.0 | 18.7 | 20.1 | 21.8 | 24.2 | 26.4 | 30.6 |
| 56 | 3.9 | 6.1 | 7.2 | 8.5 | 9.3 | 10.0 | 13.0 | 18.8 | 20.1 | 21.8 | 24.3 | 26.5 | 30.8 |
| 57 | 3.9 | 6.1 | 7.2 | 8.5 | 9.3 | 10.0 | 13.0 | 18.8 | 20.2 | 21.9 | 24.4 | 26.6 | 30.9 |
| 58 | 3.9 | 6.0 | 7.2 | 8.4 | 9.3 | 10.0 | 13.0 | 18.9 | 20.2 | 22.0 | 24.5 | 26.7 | 31.0 |
| 59 | 3.8 | 6.0 | 7.1 | 8.4 | 9.3 | 10.0 | 13.0 | 18.9 | 20.3 | 22.0 | 24.6 | 26.8 | 31.2 |
| 60 | 3.8 | 6.0 | 7.1 | 8.4 | 9.3 | 10.0 | 13.0 | 19.0 | 20.4 | 22.1 | 24.7 | 26.9 | 31.3 |
| 61 | 3.8 | 6.0 | 7.1 | 8.4 | 9.3 | 10.0 | 13.0 | 19.0 | 20.4 | 22.2 | 24.8 | 27.0 | 31.4 |
| 62 | 3.7 | 6.0 | 7.1 | 8.4 | 9.3 | 10.0 | 13.0 | 19.1 | 20.5 | 22.2 | 24.9 | 27.1 | 31.6 |
| 63 | 3.7 | 5.9 | 7.1 | 8.4 | 9.3 | 10.0 | 13.0 | 19.1 | 20.5 | 22.3 | 25.0 | 27.2 | 31.7 |
| 64 | 3.7 | 5.9 | 7.1 | 8.4 | 9.3 | 10.0 | 13.0 | 19.2 | 20.6 | 22.4 | 25.1 | 27.4 | 31.9 |
| 65 | 3.7 | 5.9 | 7.0 | 8.4 | 9.3 | 10.0 | 13.0 | 19.2 | 20.7 | 22.5 | 25.1 | 27.5 | 32.0 |
| 66 | 3.6 | 5.9 | 7.0 | 8.4 | 9.2 | 10.0 | 13.0 | 19.3 | 20.7 | 22.5 | 25.2 | 27.6 | 32.1 |
| 67 | 3.6 | 5.9 | 7.0 | 8.3 | 9.2 | 10.0 | 13.0 | 19.3 | 20.8 | 22.6 | 25.3 | 27.7 | 32.3 |
| 68 | 3.6 | 5.8 | 7.0 | 8.3 | 9.2 | 10.0 | 13.1 | 19.4 | 20.8 | 22.7 | 25.4 | 27.8 | 32.4 |
| 69 | 3.5 | 5.8 | 7.0 | 8.3 | 9.2 | 9.9 | 13.1 | 19.4 | 20.9 | 22.8 | 25.5 | 27.9 | 32.6 |
| 70 | 3.5 | 5.8 | 7.0 | 8.3 | 9.2 | 9.9 | 13.1 | 19.5 | 21.0 | 22.8 | 25.6 | 28.0 | 32.7 |
| 71 | 3.5 | 5.8 | 6.9 | 8.3 | 9.2 | 9.9 | 13.1 | 19.5 | 21.0 | 22.9 | 25.7 | 28.1 | 32.9 |
| 72 | 3.5 | 5.8 | 6.9 | 8.3 | 9.2 | 9.9 | 13.1 | 19.6 | 21.1 | 23.0 | 25.8 | 28.2 | 33.0 |
| 73 | 3.4 | 5.7 | 6.9 | 8.3 | 9.2 | 9.9 | 13.1 | 19.6 | 21.2 | 23.1 | 25.9 | 28.3 | 33.1 |
| 74 | 3.4 | 5.7 | 6.9 | 8.3 | 9.2 | 9.9 | 13.1 | 19.7 | 21.2 | 23.1 | 26.0 | 28.5 | 33.3 |
| 75 | 3.4 | 5.7 | 6.9 | 8.3 | 9.2 | 9.9 | 13.1 | 19.7 | 21.3 | 23.2 | 26.1 | 28.6 | 33.4 |
| 76 | 3.4 | 5.7 | 6.9 | 8.3 | 9.2 | 9.9 | 13.1 | 19.8 | 21.3 | 23.3 | 26.2 | 28.7 | 33.6 |
| 77 | 3.3 | 5.7 | 6.9 | 8.3 | 9.2 | 9.9 | 13.1 | 19.9 | 21.4 | 23.4 | 26.3 | 28.8 | 33.7 |
| 78 | 3.3 | 5.7 | 6.9 | 8.2 | 9.2 | 9.9 | 13.1 | 19.9 | 21.5 | 23.4 | 26.4 | 28.9 | 33.8 |
| 79 | 3.3 | 5.6 | 6.8 | 8.2 | 9.2 | 9.9 | 13.1 | 20.0 | 21.5 | 23.5 | 26.5 | 29.0 | 34.0 |
| 80 | 3.3 | 5.6 | 6.8 | 8.2 | 9.2 | 9.9 | 13.2 | 20.0 | 21.6 | 23.6 | 26.5 | 29.1 | 34.1 |
| 81 | 3.2 | 5.6 | 6.8 | 8.2 | 9.2 | 9.9 | 13.2 | 20.1 | 21.7 | 23.7 | 26.6 | 29.2 | 34.3 |
| 82 | 3.2 | 5.6 | 6.8 | 8.2 | 9.2 | 9.9 | 13.2 | 20.1 | 21.7 | 23.7 | 26.7 | 29.3 | 34.4 |
| 83 | 3.2 | 5.6 | 6.8 | 8.2 | 9.2 | 9.9 | 13.2 | 20.2 | 21.8 | 23.8 | 26.8 | 29.4 | 34.5 |
| 84 | 3.2 | 5.6 | 6.8 | 8.2 | 9.2 | 9.9 | 13.2 | 20.2 | 21.8 | 23.9 | 26.9 | 29.5 | 34.7 |
| 85 | 3.1 | 5.6 | 6.8 | 8.2 | 9.2 | 9.9 | 13.2 | 20.3 | 21.9 | 24.0 | 27.0 | 29.7 | 34.8 |
| 86 | 3.1 | 5.5 | 6.8 | 8.2 | 9.2 | 9.9 | 13.2 | 20.3 | 22.0 | 24.0 | 27.1 | 29.8 | 35.0 |
| 87 | 3.1 | 5.5 | 6.8 | 8.2 | 9.1 | 9.9 | 13.2 | 20.4 | 22.0 | 24.1 | 27.2 | 29.9 | 35.1 |
| 88 | 3.1 | 5.5 | 6.8 | 8.2 | 9.1 | 9.9 | 13.2 | 20.4 | 22.1 | 24.2 | 27.3 | 30.0 | 35.2 |
There are errors in Fig. 5 and the legend for Fig. 5. Please view the corrected Fig. 5 and the complete, correct Fig. 5 legend here.
Fig 5. The validated model in centiles.
Normative ranges for the model of total testosterone from ages 3–88 years. In the average case (red line) total testosterone remains constant for age > 40. However, the variance in normative ranges increases for these ages, with 1st to 99th centile ranges of 4.7–29.2 nmol/L at age 35 years and 3.1–35.2 nmol/L at age 88 years.
Reference
- 1. Kelsey TW, Li LQ, Mitchell RT, Whelan A, Anderson RA, et al. (2014) A Validated Age-Related Normative Model for Male Total Testosterone Shows Increasing Variance but No Decline after Age 40 Years. PLoS ONE 9(10): e109346 doi: 10.1371/journal.pone.0109346 [DOI] [PMC free article] [PubMed] [Google Scholar]

