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. 2015 Feb 6;10(2):e0117674. doi: 10.1371/journal.pone.0117674

Correction: A Validated Age-Related Normative Model for Male Total Testosterone Shows Increasing Variance but No Decline after Age 40 Years

The PLOS ONE Staff
PMCID: PMC4319902  PMID: 25658880

There are errors in Table 3. Please view the corrected Table 3 here.

Table 3. Normative age-related total testosterone reference values in nmol/L.

Ages are in years; column headings are percentiles.

Age 1 2.5 10 20 30 40 50 60 70 80 90 97.5 99
3 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.6 0.6 0.7 0.8 0.9 1.0
4 0.0 0.0 0.1 0.1 0.2 0.2 0.4 0.6 0.6 0.7 0.8 0.9 1.0
5 0.0 0.0 0.1 0.1 0.2 0.2 0.4 0.6 0.6 0.7 0.8 0.8 1.0
6 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.5 0.6 0.6 0.7 0.8 0.9
7 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.5 0.5 0.6 0.7 0.7 0.9
8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.5 0.5 0.6 0.7 0.9
9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.5 0.6 0.7 0.8 1.0
10 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.7 0.8 0.9 1.0 1.2 1.4
11 0.0 0.0 0.0 0.2 0.3 0.3 0.7 1.3 1.4 1.6 1.9 2.1 2.6
12 0.0 0.3 0.5 0.8 1.0 1.1 1.7 2.8 3.1 3.4 3.9 4.3 5.2
13 0.6 1.4 1.7 2.2 2.5 2.7 3.8 5.9 6.4 7.0 8.0 8.8 10.3
14 1.8 3.0 3.6 4.4 4.8 5.2 6.9 10.5 11.4 12.4 14.0 15.3 18.0
15 2.9 4.6 5.6 6.6 7.3 7.9 10.3 15.4 16.5 18.0 20.2 22.1 25.9
16 3.7 5.9 7.0 8.3 9.2 9.8 12.9 19.0 20.4 22.2 24.9 27.2 31.7
17 4.1 6.6 7.8 9.3 10.3 11.1 14.4 21.1 22.6 24.6 27.5 30.0 34.9
18 4.4 7.0 8.3 9.8 10.8 11.7 15.2 22.0 23.6 25.6 28.5 31.1 36.1
19 4.6 7.2 8.5 10.0 11.1 11.9 15.4 22.2 23.7 25.7 28.6 31.1 36.1
20 4.7 7.3 8.6 10.1 11.1 11.9 15.4 21.9 23.5 25.4 28.2 30.7 35.5
21 4.8 7.3 8.6 10.0 11.0 11.8 15.2 21.6 23.0 24.9 27.6 30.0 34.7
22 4.9 7.3 8.5 10.0 10.9 11.7 15.0 21.2 22.6 24.4 27.0 29.3 33.8
23 4.9 7.3 8.5 9.9 10.8 11.5 14.8 20.7 22.1 23.9 26.4 28.7 33.1
24 4.9 7.2 8.4 9.8 10.7 11.4 14.5 20.4 21.7 23.4 25.9 28.1 32.3
25 4.9 7.2 8.3 9.7 10.6 11.3 14.3 20.0 21.3 23.0 25.4 27.6 31.7
26 5.0 7.2 8.3 9.6 10.4 11.1 14.1 19.7 21.0 22.6 25.0 27.1 31.2
27 4.9 7.1 8.2 9.5 10.3 11.0 14.0 19.5 20.7 22.3 24.7 26.7 30.7
28 4.9 7.1 8.2 9.4 10.3 10.9 13.8 19.2 20.5 22.1 24.4 26.4 30.4
29 4.9 7.0 8.1 9.3 10.2 10.8 13.7 19.1 20.3 21.8 24.2 26.2 30.1
30 4.9 7.0 8.0 9.3 10.1 10.8 13.6 18.9 20.1 21.7 24.0 25.9 29.8
31 4.9 6.9 8.0 9.2 10.0 10.7 13.5 18.8 20.0 21.5 23.8 25.8 29.6
32 4.8 6.9 7.9 9.1 10.0 10.6 13.4 18.7 19.9 21.4 23.7 25.6 29.4
33 4.8 6.8 7.9 9.1 9.9 10.6 13.3 18.6 19.8 21.3 23.6 25.5 29.3
34 4.8 6.8 7.8 9.0 9.9 10.5 13.3 18.5 19.7 21.2 23.5 25.4 29.2
35 4.7 6.8 7.8 9.0 9.8 10.5 13.2 18.4 19.6 21.2 23.4 25.4 29.2
36 4.7 6.7 7.8 9.0 9.8 10.4 13.2 18.4 19.6 21.1 23.4 25.3 29.1
37 4.7 6.7 7.7 8.9 9.7 10.4 13.1 18.4 19.6 21.1 23.3 25.3 29.1
38 4.6 6.7 7.7 8.9 9.7 10.3 13.1 18.3 19.5 21.1 23.3 25.3 29.1
39 4.6 6.6 7.7 8.9 9.7 10.3 13.1 18.3 19.5 21.1 23.3 25.3 29.1
40 4.5 6.6 7.6 8.8 9.6 10.3 13.0 18.3 19.5 21.1 23.3 25.3 29.2
41 4.5 6.5 7.6 8.8 9.6 10.2 13.0 18.3 19.5 21.1 23.4 25.3 29.2
42 4.5 6.5 7.6 8.8 9.6 10.2 13.0 18.3 19.6 21.1 23.4 25.4 29.3
43 4.4 6.5 7.5 8.7 9.5 10.2 13.0 18.3 19.6 21.1 23.4 25.4 29.3
44 4.4 6.4 7.5 8.7 9.5 10.2 13.0 18.4 19.6 21.2 23.5 25.5 29.4
45 4.4 6.4 7.5 8.7 9.5 10.2 13.0 18.4 19.6 21.2 23.5 25.6 29.5
46 4.3 6.4 7.4 8.7 9.5 10.1 13.0 18.4 19.7 21.2 23.6 25.6 29.6
47 4.3 6.3 7.4 8.6 9.5 10.1 13.0 18.4 19.7 21.3 23.6 25.7 29.7
48 4.2 6.3 7.4 8.6 9.4 10.1 13.0 18.5 19.7 21.3 23.7 25.8 29.8
49 4.2 6.3 7.4 8.6 9.4 10.1 13.0 18.5 19.8 21.4 23.8 25.9 29.9
50 4.2 6.3 7.3 8.6 9.4 10.1 13.0 18.5 19.8 21.4 23.9 25.9 30.0
51 4.1 6.2 7.3 8.6 9.4 10.1 13.0 18.6 19.9 21.5 23.9 26.0 30.1
52 4.1 6.2 7.3 8.5 9.4 10.1 13.0 18.6 19.9 21.6 24.0 26.1 30.3
53 4.0 6.2 7.3 8.5 9.4 10.0 13.0 18.6 20.0 21.6 24.1 26.2 30.4
54 4.0 6.2 7.2 8.5 9.4 10.0 13.0 18.7 20.0 21.7 24.2 26.3 30.5
55 4.0 6.1 7.2 8.5 9.3 10.0 13.0 18.7 20.1 21.8 24.2 26.4 30.6
56 3.9 6.1 7.2 8.5 9.3 10.0 13.0 18.8 20.1 21.8 24.3 26.5 30.8
57 3.9 6.1 7.2 8.5 9.3 10.0 13.0 18.8 20.2 21.9 24.4 26.6 30.9
58 3.9 6.0 7.2 8.4 9.3 10.0 13.0 18.9 20.2 22.0 24.5 26.7 31.0
59 3.8 6.0 7.1 8.4 9.3 10.0 13.0 18.9 20.3 22.0 24.6 26.8 31.2
60 3.8 6.0 7.1 8.4 9.3 10.0 13.0 19.0 20.4 22.1 24.7 26.9 31.3
61 3.8 6.0 7.1 8.4 9.3 10.0 13.0 19.0 20.4 22.2 24.8 27.0 31.4
62 3.7 6.0 7.1 8.4 9.3 10.0 13.0 19.1 20.5 22.2 24.9 27.1 31.6
63 3.7 5.9 7.1 8.4 9.3 10.0 13.0 19.1 20.5 22.3 25.0 27.2 31.7
64 3.7 5.9 7.1 8.4 9.3 10.0 13.0 19.2 20.6 22.4 25.1 27.4 31.9
65 3.7 5.9 7.0 8.4 9.3 10.0 13.0 19.2 20.7 22.5 25.1 27.5 32.0
66 3.6 5.9 7.0 8.4 9.2 10.0 13.0 19.3 20.7 22.5 25.2 27.6 32.1
67 3.6 5.9 7.0 8.3 9.2 10.0 13.0 19.3 20.8 22.6 25.3 27.7 32.3
68 3.6 5.8 7.0 8.3 9.2 10.0 13.1 19.4 20.8 22.7 25.4 27.8 32.4
69 3.5 5.8 7.0 8.3 9.2 9.9 13.1 19.4 20.9 22.8 25.5 27.9 32.6
70 3.5 5.8 7.0 8.3 9.2 9.9 13.1 19.5 21.0 22.8 25.6 28.0 32.7
71 3.5 5.8 6.9 8.3 9.2 9.9 13.1 19.5 21.0 22.9 25.7 28.1 32.9
72 3.5 5.8 6.9 8.3 9.2 9.9 13.1 19.6 21.1 23.0 25.8 28.2 33.0
73 3.4 5.7 6.9 8.3 9.2 9.9 13.1 19.6 21.2 23.1 25.9 28.3 33.1
74 3.4 5.7 6.9 8.3 9.2 9.9 13.1 19.7 21.2 23.1 26.0 28.5 33.3
75 3.4 5.7 6.9 8.3 9.2 9.9 13.1 19.7 21.3 23.2 26.1 28.6 33.4
76 3.4 5.7 6.9 8.3 9.2 9.9 13.1 19.8 21.3 23.3 26.2 28.7 33.6
77 3.3 5.7 6.9 8.3 9.2 9.9 13.1 19.9 21.4 23.4 26.3 28.8 33.7
78 3.3 5.7 6.9 8.2 9.2 9.9 13.1 19.9 21.5 23.4 26.4 28.9 33.8
79 3.3 5.6 6.8 8.2 9.2 9.9 13.1 20.0 21.5 23.5 26.5 29.0 34.0
80 3.3 5.6 6.8 8.2 9.2 9.9 13.2 20.0 21.6 23.6 26.5 29.1 34.1
81 3.2 5.6 6.8 8.2 9.2 9.9 13.2 20.1 21.7 23.7 26.6 29.2 34.3
82 3.2 5.6 6.8 8.2 9.2 9.9 13.2 20.1 21.7 23.7 26.7 29.3 34.4
83 3.2 5.6 6.8 8.2 9.2 9.9 13.2 20.2 21.8 23.8 26.8 29.4 34.5
84 3.2 5.6 6.8 8.2 9.2 9.9 13.2 20.2 21.8 23.9 26.9 29.5 34.7
85 3.1 5.6 6.8 8.2 9.2 9.9 13.2 20.3 21.9 24.0 27.0 29.7 34.8
86 3.1 5.5 6.8 8.2 9.2 9.9 13.2 20.3 22.0 24.0 27.1 29.8 35.0
87 3.1 5.5 6.8 8.2 9.1 9.9 13.2 20.4 22.0 24.1 27.2 29.9 35.1
88 3.1 5.5 6.8 8.2 9.1 9.9 13.2 20.4 22.1 24.2 27.3 30.0 35.2

There are errors in Fig. 5 and the legend for Fig. 5. Please view the corrected Fig. 5 and the complete, correct Fig. 5 legend here.

Fig 5. The validated model in centiles.

Fig 5

Normative ranges for the model of total testosterone from ages 3–88 years. In the average case (red line) total testosterone remains constant for age > 40. However, the variance in normative ranges increases for these ages, with 1st to 99th centile ranges of 4.7–29.2 nmol/L at age 35 years and 3.1–35.2 nmol/L at age 88 years.

Reference


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