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. 1977 Nov;74(11):4905–4908. doi: 10.1073/pnas.74.11.4905

Isopeptide linkage between N-alpha-monomethylalanine and lysine in ribosomal protein S11 from Escherichia coli.

R Chen, U Chen-Schmeisser
PMCID: PMC432065  PMID: 337304

Abstract

Protein S11 from the Escherichia coli ribosome has a unique NH2-terminal structure not previously observed among ribosomal proteins. Owing to the formation of an isopeptide bond between a secondary amino acid (N-alpha-monomethylalanine) and the epsilon-amino group of the NH2-terminal lysine residue, a "branching point" is formed. Therefore, two amino acids are seen when the NH2 terminus of the protein is determined.

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Selected References

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