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. 1977 Jun;74(6):2241–2245. doi: 10.1073/pnas.74.6.2241

Uncouplers and the molecular mechanism of uncoupling in mitochondria.

R J Kessler, H Vande Zande, C A Tyson, G A Blondin, J Fairfield, P Glasser, D E Green
PMCID: PMC432145  PMID: 142250

Abstract

Uncouplers are molecules with protonophoric and ionophoric capabilities that mediate coupled cyclical transport of cations--a transport that takes precedence over all other coupled processes. Uncouplers form cation-containing complexes with electrogenic ionophores that potentiate cyclical transport of cations. The molecular mechanism of uncoupling sheds strong light on the mechanism of coupling.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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