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. 1977 Jun;74(6):2283–2287. doi: 10.1073/pnas.74.6.2283

Inactivation and proteolytic cleavage of phage lambda repressor in vitro in an ATP-dependent reaction.

J W Roberts, C W Roberts, D W Mount
PMCID: PMC432154  PMID: 329277

Abstract

We have reproduced in vitro the inactivation of bacteriophage lambda repressor that occurs in vivo when a lambda lysogen is treated with agents such as ultraviolet radiation that attack DNA. ATP and a divalent cation are required for the inactivation reaction. The ind- repressor is insensitive to the inactivation mechanism. A proteolytic cleavage of repressor accompanies inactivation in vitro, as it does in vivo.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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