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. Author manuscript; available in PMC: 2015 Feb 10.
Published in final edited form as: J Am Chem Soc. 2014 Oct 6;136(41):14626. doi: 10.1021/ja509209d

Correction to “Merochlorins A-D, cyclic meroterpenoid antibiotics biosynthesized in divergent pathways with vanadium-dependent chloroperoxidases”

Leonard Kaysser 1, Peter Bernhardt 2, Sang-Jip Nam 3, Sandra Loesgen 4, J Graham Ruby 5, Peter Skewes-Cox 6, Paul R Jensen 7, William Fenical 8, Bradley S Moore 9
PMCID: PMC4321864  NIHMSID: NIHMS633609

Page 11988. The statement “to unambiguously establish its absolute configuration, we solved the crystal structure of a methylated and acetylated derivative of 1 (Figure 1B)” is incorrect. While the crystal structure confirmed the relative configuration of merochlorin A (1), because it was later found to be in a centrosymmetric monoclinic space group, its absolute configuration could not be assigned.

Page 11989. In Figure 1, two stereocenters of merochlorin A are drawn incorrectly. The corrected structure is shown below.

graphic file with name nihms-633609-f0001.jpg

Page 11989. The Figure 1B caption is revised to “Oak Ridge Thermal Ellipsoid Plot (ORTEP) representation of the X-ray structure of 3-acetyl-5-methyl-merochlorin A” without mention of absolute stereochemical determination per the above correction.

A revised Supporting Information document is available that corrects the merochlorin A structure drawing, NMR chemical shifts (1H and 13C) in Tables S1, S2 and S3 as well as in the text describing the structure assignments (pages S7-S13), and exchanged the 1D NMR spectra with the properly referenced and labeled spectra (Figures S1, S2, S7, S8, S13, S14, S15, S16).

Supplementary Material

002

Footnotes

Supporting Information.

Experimental section, supporting tables, detailed compound characterization, and crystallographic data are provided. This material is available free of charge via the Internet at http://pubs.acs.org.

Contributor Information

Leonard Kaysser, University of Tuebingen, Pharmaceutical Biology.

Peter Bernhardt, Shire HGT.

Sang-Jip Nam, Ewha Womans University, Chemistry and Nano Science.

Sandra Loesgen, Oregon State University, Chemistry.

J. Graham Ruby, University of California at San Francisco, Department of Biochemistry and Biophysics.

Peter Skewes-Cox, University of California at San Francisco, Department of Biochemistry and Biophysics.

Paul R. Jensen, University of California San Diego, Scripps Institution of Oceanography

William Fenical, University of California, San Diego, Scripps Institution of Oceanography.

Bradley S. Moore, University of California at San Diego, Scripps Institution of Oceanography

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

002
NIHMS633609-supplement-002.pdf (2.1MB, pdf)

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