FIG. 4.

Comparison between the whole and the euthyroid subsample. Top: Estimated mean levels of serum glucose, HbA1c, HOMA-IR, and insulin with 95% confidence intervals by serum 3,5-diiodothyronine concentrations calculated by ANOVA adjusted for age and sex. p_whole and p_eut, p-values from ANOVA about an overall difference between groups in the whole and euthyroid sample, respectively. Significant differences between groups were marked for comparison with the ^†lowest and ^‡intermediate (p<0.05). Bottom: Predicted mean level of the same parameters conditioned on 3,5-diiodothyronine serum concentrations >0.2 nM for a 50-year-old man from linear regression analysis. Corresponding p-values are listed in Table 2. HOMA-IR, homeostatic model of insulin resistance; HbA1c, glycosylated hemoglobin.