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Colonic mucosal PGE2 levels (in ng/mg protein) in 15-PGDH WT FVB mice (open bars) that are: untreated (control, n = 5), or treated with celecoxib (n = 5), aspirin (n = 5) or sulindac (n = 5); versus FVB 15-PGDH KO mice (black bars) that are: untreated (control, n = 7), or treated with celecoxib (n = 5), aspirin (n = 4) or sulindac (n = 3). Error bars designate standard error of the mean.
