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. 1975 Jan;72(1):103–107. doi: 10.1073/pnas.72.1.103

Xeroderma pigmentosum cells contain low levels of photoreactivating enzyme.

B M Sutherland, M Rice, E K Wagner
PMCID: PMC432249  PMID: 1054487

Abstract

Fibroblasts from patients with xeroderma pigmentosum contain low levels of photoreactivating enzyme in comparison to normal cells. Levels vary from 0 (line 1199) to 50 (line 1259) percent of normal. The depressed enzyme levels are not an artifact of low growth rate, age of cell donor, cell culture conditions, assay conditions, the presence of inhibitors, or mycoplasma contamination. We show that human fibroblasts can monomerize pyrimidine dimers in vivo.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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