Abstract
Lamellar neutron diffraction from oriented multilayers of hydrated dipalmitoyl lecithin was phased by isomorphous H2O-D2O exchange and swelling techniques. Bound water sites were located in the polar head group region of the bilayer profile. A 6-Å resolution structure based on the neutron scattering density profile is proposed for the bilayer. It is consistent with the electron density profile from x-ray diffraction.
Keywords: membrane structure, bound water, H2O-D2O exchange, phospholipid bilayer
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