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. 1975 Mar;72(3):829–833. doi: 10.1073/pnas.72.3.829

Replicative intermediates of colicin E1 plasmid DNA in minicells.

A Oka, J Inselburg
PMCID: PMC432413  PMID: 1093172

Abstract

Pulse-labeled colicin E1 plasmid (Col E1) DNA in minicells was examined to characterize replicating molecules. Replication of Col E1 DNA principally occurred in covalently closed molecules and involved the synthesis of variable length single-stranded DNA fragments that were dissociable from the template DNA and ultimately incorporated into the completely replicated molecules. RNA was found to be associated with some of these newly synthesized fragments. Replicating molecules containing different size displacement loops were observed by electron microscopy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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