Below is the answer to the quiz by Dr. Şenel et al presented in the previous issue of Dermatology Practical & Conceptual [2014;4(4):13].
Diagnosis: Kaposi sarcoma.
Kaposi sarcoma (KS) was first described by Kaposi in 1872. There are four clinical types of the disease: classic, endemic, epidemic and iatrogenic [1]. Iatrogenic KS develops in patients taking immunosuppressive treatment. Bluish-reddish coloration is seen in 84% of KS lesions in dermatoscopy. Rainbow pattern and scaly surface are other dermatoscopic features of KS (36% and 15%, respectively) [2]. Multicolored rainbow pattern is the most diagnostic appearance of KS in dermatoscopic evaluation and is associated with vascular lumen-rich histological sub-type [3]. This pattern can be rarely seen in the dermatoscopy of melanoma [4].
Congratulations to Dr. Arina Vashkevich (aavashk@mail.ru), who was the first to send us the correct answer!
References
- 1.Ahmadpoor P. Human herpesvirus-8 and Kaposi sarcoma after kidney transplantation: mechanisms of tumor genesis. Iran J Kid Dis. 2009;3(3):121–26. [PubMed] [Google Scholar]
- 2.Hu SC, Ke CL, Lee CH, et al. Dermoscopy of Kaposi's sarcoma: areas exhibiting the multicoloured ‘rainbow pattern’. J Eur Acad Dermatol Venereol. 2009;23(10):1128–32. doi: 10.1111/j.1468-3083.2009.03239.x. [DOI] [PubMed] [Google Scholar]
- 3.Şenel E. Dermatoscopy of non-melanocytic skin tumors. Indian J Dermatol Venereol Leprol. 2011;77(1):16–21. doi: 10.4103/0378-6323.74966. quiz 22. [DOI] [PubMed] [Google Scholar]
- 4.Cheng ST, Ke CL, Lee CH, et al. Rainbow pattern in Kaposi's sarcoma under polarized dermoscopy: a dermoscopic pathological study. Br J Dermatol. 2009;160(4):801–9. doi: 10.1111/j.1365-2133.2008.08940.x. [DOI] [PubMed] [Google Scholar]