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The effect of diazepam and COX-2 inhibitor, NS-398, on neuronal damage 24 h after pilocarpine-induced SE. When diazepam was injected alone (SE + Diazepam, 10 mg/kg, n = 8), it did not cause significant neuroprotection compared to the vehicle group (SE + vehicle, n = 9). When diazepam was administered together with NS-398 (10 mg/kg each, n = 8), significant neuroprotection was observed in the CA1, CA3 and hilus of the dentate gyrus (* p<0.05).
