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European Journal of Human Genetics logoLink to European Journal of Human Genetics
. 2015 Feb 12;23(3):416. doi: 10.1038/ejhg.2014.152

A defect in the CLIP1 gene (CLIP-170) can cause autosomal recessive intellectual disability

Farzaneh Larti, Kimia Kahrizi, Luciana Musante, Hao Hu, Elahe Papari, Zohreh Fattahi, Niloofar Bazazzadegan, Zhe Liu, Mehdi Banan, Masoud Garshasbi, Thomas F Wienker, H Hilger Ropers, Niels Galjart, Hossein Najmabadi
PMCID: PMC4326717  PMID: 25672248

Correction to: European Journal of Human Genetics advance online publication 26 February 2014; doi: 10.1038/ejhg.2014.13

Upon revisiting their published work on a defect in the CLIP1 gene, the authors noted that the brain MRI obtained from the affected girl (IV: 7), which was reported to be normal at that time, showed a local white matter around fornices with abnormal signal of the frontal horns' ‘focal leukoencephalopathy'. They would like to report focal leukodystrophy in the brain MRI of the patient with CLIP1 mutation as a migration role of this gene in cortical neurons (Figure 1).

Figure 1.

Figure 1

(a) Axial section of flair showed local white matter around fornices with abnormal signal of frontal horns ‘focal leukodystrophy'.


Articles from European Journal of Human Genetics are provided here courtesy of Nature Publishing Group

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