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. 1975 Jul;72(7):2626–2630. doi: 10.1073/pnas.72.7.2626

An octamer of histones in chromatin and free in solution.

J O Thomas, R D Kornberg
PMCID: PMC432822  PMID: 241077

Abstract

Crosslinking with dimethyl suberimidate reveals a chain of histone octamers in chromatin. The octamer can be isolated free in solution at high ionic strength and pH. The identification of dimers formed by crosslinking reveals two or more contacts of each histone with others within the octamer. The molecular weight (110,000) and pattern of dissociation of the octamer are compatible with the composition (F2A1)2(F3)2(F2A2)2(F2B)2.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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