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. 1975 Sep;72(9):3347–3350. doi: 10.1073/pnas.72.9.3347

Identification of the 5' end of Rous sarcoma virus RNA.

J Keith, H Fraenkel-Conrat
PMCID: PMC432989  PMID: 171660

Abstract

The 5'-terminal triphosphate of the 35S RNA isolated from Rous sarcoma virus is blocked by 7-methylguanosine in 5' linkage with the penultimate nucleoside which is methylated in the 2'-O-ribose position, a type of endgroup found in all animal mRNAs investigated during the past year. The specific nuclease-resistant terminal fragment of RSV RNA has the structure 7mG5'ppp5'GmpCp-. This finding supports the belief that RNA of Rous sarcoma virus represents a (+) strand messenger which may be directly translated upon infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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