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. 2014 Dec 29;156(3):1111–1120. doi: 10.1210/en.2014-1851

Figure 2.

Figure 2.

E2 increases Kiss1 mRNA expression in the AVPV of OVX WT and, to a lesser extent, KERαKO mice. A, Representative photomicrographs of Kiss1 mRNA expression in the AVPV of WT (left panels) and KERαKO (right panels) mice at Bregma 0.26 (21). Mice were bilaterally OVX and implanted with a capsule containing vehicle (V) or E2. Brains were collected 7 days after OVX. B, Mean signal intensity of Kiss1 mRNA expression in the AVPV. Scale bar = 100 μm. ***, P < .001 compared with V-treated mice. All data represented as mean ± SEM.