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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1975 Sep;72(9):3619–3622. doi: 10.1073/pnas.72.9.3619

A mechanism for initiation of genetic recombination.

R E Wagner Jr, M Radman
PMCID: PMC433047  PMID: 1059151

Abstract

A mechanism for the initiation of genetic recombination is proposed. Its key features are the pairing, nicking, and cross-annealing of palindromic loops, i.e., structures formed by DNA with sequences of inverted complementary repeats. This mechanism may provide a simple, yet specific means of producing crossed strand connections between homologous DNA duplexes to form structures which can be intermediates in the process of genetic recombination.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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