Abstract
Antibody to homogeneous terminal deoxynucleotidyl transferase (EC 2.7.7.31, nucleoside triphosphate: DNA deoxynucleotidylexotransferase) from calf thymus gland has been prepared using crosslinked antigen derivatives in rabbits. The antisera produced precipitate and neutralize homologous antigen, and crossreact with human, chicken, mouse, and rat terminal transferase. Antiserum to pure terminal transferase provides greatly expanded analytical capabilities for further studies on terminal transferase biology and structure.
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- Chang L. M., Bollum F. J. Deoxynucleotide-polymerizing enzymes of calf thymus gland. V. Homogeneous terminal deoxynucleotidyl transferase. J Biol Chem. 1971 Feb 25;246(4):909–916. [PubMed] [Google Scholar]
- Chang L. M. Development of terminal deoxynucleotidyl transferase activity in embryonic calf thymus gland. Biochem Biophys Res Commun. 1971 Jul 2;44(1):124–131. doi: 10.1016/s0006-291x(71)80167-5. [DOI] [PubMed] [Google Scholar]
- Coleman M. S., Hutton J. J., De Simone P., Bollum F. J. Terminal deoxyribonucleotidyl transferase in human leukemia. Proc Natl Acad Sci U S A. 1974 Nov;71(11):4404–4408. doi: 10.1073/pnas.71.11.4404. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kung P. C., Siverstone A. E., McCaffrey R. P., Baltimore D. Murine terminal deoxynucleotidyl transferase: cellular distribution and response to cortisone. J Exp Med. 1975 Apr 1;141(4):855–865. [PMC free article] [PubMed] [Google Scholar]
- LAMPKIN J. M., POTTER M. Response to cortisone and development of cortisone resistance in a cortisone-sensitive lymphosarcoma of the mouse. J Natl Cancer Inst. 1958 Jun;20(6):1091–1111. doi: 10.1093/jnci/20.6.1091. [DOI] [PubMed] [Google Scholar]
- Laemmli U. K., Favre M. Maturation of the head of bacteriophage T4. I. DNA packaging events. J Mol Biol. 1973 Nov 15;80(4):575–599. doi: 10.1016/0022-2836(73)90198-8. [DOI] [PubMed] [Google Scholar]
- McCaffrey R., Smoler D. F., Baltimore D. Terminal deoxynucleotidyl transferase in a case of childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A. 1973 Feb;70(2):521–525. doi: 10.1073/pnas.70.2.521. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Reichlin M., Fogel S., Nisonoff A., Margoliash E. Antibodies against cytochromes c from vertebrates. J Biol Chem. 1966 Jan 10;241(1):251–253. [PubMed] [Google Scholar]
- Sarin P. S., Gallo R. C. Terminal deoxynucleotidyltransferase in chronic myelogenous leukemia. J Biol Chem. 1974 Dec 25;249(24):8051–8053. [PubMed] [Google Scholar]