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. 1973 Jan;70(1):11–14. doi: 10.1073/pnas.70.1.11

In Situ Hybridization of RD114-Virus RNA with Human Metaphase Chromosomes

Peter M Price *, Kurt Hirschhorn *, Norman Gabelman , Samuel Waxman
PMCID: PMC433172  PMID: 4119221

Abstract

In situ hybridization was used to detect regions of human metaphase chromosomes exhibiting complementarity with radioactively-labeled RNA isolated from RD114-virus. The region of homology, as identified by autoradiography, was confined to one D-group chromosome.

Keywords: density gradient centrifugation, karyotype, RNA-dependent DNA polymerase

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Selected References

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