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. 1973 Jan;70(1):54–56. doi: 10.1073/pnas.70.1.54

Production of Mucopolysaccharides by Normal and Transformed Cells

C Satoh 1,2, R Duff 1,2, F Rapp 1,2, E A Davidson 1,2,*
PMCID: PMC433182  PMID: 4346038

Abstract

The rate of hyaluronic acid and sulfated mucopolysaccharide production was measured for hamster embryo fibroblasts and for general oncogenic lines derived by virus transformation. A striking increase in both the rate of hyaluronic acid synthesis and the amount of cell-associated polymer was observed after transformation by herpes simplex type-2 or SV40 virus. Although no corresponding change was observed for the sulfated polysaccharides, the proportion of heparan sulfate increased significantly after transformation.

Keywords: hyaluronic acid, transformed cells, hamster-embryo cultures

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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