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. 1973 Jun;70(6):1894–1897. doi: 10.1073/pnas.70.6.1894

Glia-Induced Morphological Differentiation in Neuroblastoma Cells

Denis Monard 1, Frank Solomon 1, Magda Rentsch 1, Reinhard Gysin 1
PMCID: PMC433621  PMID: 4352661

Abstract

Glial cells release a factor into their culture medium that induces a high degree of morphological differentiation in neuroblastoma cells under normal growth conditions. This phenomenon is not correlated with a change in intracellular adenosine 3′:5′-cyclic monophosphate or in the rate of cell growth. Media from other cell lines tested induce less morphological differentiation or have no effect.

Keywords: glial-neuronal interactions

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Selected References

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